Resume | Brandon S. Russell, Ph.D.

Summary

A decade of medical science liaison experience across a portfolio of new and established medicines
Six years of biomedical research with broad expertise in infection, inflammation, and immunology
Three years working as an EMT delivering hands-on patient care and liaising with healthcare providers
Co-author of five peer-reviewed articles exploring the quantitative biochemistry of disease processes
Award-winning public speaker with a superior ability to make complex data accessible and exciting

Massachusetts Institute of Technology, School of Engineering | Cambridge, MA (2014)

Ph.D. in Biological Engineering (Immunology)

Minor in Global Health from MIT Sloan School of Management and Harvard Medical School
Doctoral Thesis: Modified Nucleic Acids in Bacterial Pathogens – Impact on Pathogenesis, Diagnosis, and Therapy

University of Mississippi, Sally McDonnell Barksdale Honors College | Oxford, MS (2008)

B.S. in Chemistry, Magna Cum Laude, Barksdale Honors Scholar

Honors Thesis: DNA Damage and Cytotoxicity in Human Colon Cells Exposed to Toxic Doses of Nitric Oxide

GSK | Houston, TX (07/2014 – Present)

Senior Medical Science Liaison, Respiratory Portfolio (04/2021 – Present)

Medical Science Liaison, Respiratory Portfolio (07/2014 – 04/2021)

Responsible for all medical affairs engagements for asthma and COPD medicines in south Texas
Identify, engage, and build rapport with experts to understand respiratory therapeutic landscape
Serve as immunology subject matter expert for disease state and therapeutic mechanism training

MIT Biological Engineering Laboratory of Peter C. Dedon | Cambridge, MA (09/2008 – 07/2014)

Graduate Research Fellow

Discovered and characterized a novel possible mechanism of transferrable, DNA modification-mediated antibiotic resistance (published in Nature Chemical Biology)
Discovered novel tRNA-mediated stress responses by applying LC-MS/MS methods to generate quantitative systems biology data (published in Science Advances and The Journal of Immunology)
Developed new LC-MS/MS methods to identify and quantify all modified nucleic acids in any organism for stress response, biomarker, and inflammation studies (published in Nature Protocols)
Developed and characterized the immunology of a novel animal model of Mycobacterium bovis BCG lung infection for pre-clinical studies of tubercular granulomas
Supervised, trained, and mentored four junior researchers in independent projects over two years

MIT Emergency Medical Services | Cambridge, MA (04/2009 – 04/2012)

Emergency Medical Technician

Served 2 years as a Crew Chief, supervising teams of 3 EMTs and making final patient care decisions
Worked 1,800+ clinical hours on-call as an EMT-B, treating and transporting 150+ patients over 3 years

Director of Operations (04/2010 – 04/2011)

Managed a team of 50+ EMTs and oversaw equipment stocking and maintenance, patient care quality assurance, and regulatory compliance
Liaised with EMS leaders to facilitate integration of MIT's ambulance into the city 911 system, yielding a 7% increase in call volume
Created routine maintenance and incident tracking programs that reduced ambulance downtime 25%
Coordinated and led campus-wide medical coverage for 3 large public events, each with 2,000+ visitors

Candiracci J, Migeot V, Chionh YH, Bauer F, Brochier T, Russell BS, Shiozaki K, Dedon PC, Hermand D (2019) Reciprocal Regulation of TORC Signaling and tRNA Modifications by Elongator Enforces Nutrient-Dependent Cell Fate. Science Advances 5(6).
Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, Fortune S, Dedon PC, Pellegrini M, Modlin RL (2018) Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. The Journal of Immunology 200(9): 3244-3258.
Kellner S, DeMott MS, Cheng CP, Russell BS, Cao B, You D, Dedon PC (2017) Oxidation of Phosphorothioate DNA Modifications Leads to Lethal Genomic Instability. Nature Chemical Biology 13(8): 888-894.
Su D, Chan CTY, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC (2014) Quantitative Analysis of Ribonucleoside Modifications in tRNA by HPLC-Coupled Mass Spectrometry. Nature Protocols 9(4): 828-841.
Dendroulakis V, Russell BS, Elmquist CE, Trudel LJ, Wogan GN, Deen WM, Dedon PC (2012) A System for Exposing Molecules and Cells to Biologically Relevant and Accurately Controlled Steady-State Concentrations of Nitric Oxide and Oxygen. Nitric Oxide 27(3): 161-168.

MIT Medical Consumers Advisory Council | Cambridge, MA (09/2013 – 08/2014)

Graduate Student Representative

Appointed to represent a population of 4,000+ graduate students to the MIT Medical Management Board
Solicited student input, communicated criticisms, and suggested quality improvements to medical services
Created a communication channel between Graduate Student Council and medical leadership of MIT’s clinic

ClearView Healthcare Partners | Newton, MA (08/2013)

Connect-to-ClearView Summer Intern

Chosen as one of 11 out of 150 Ph.D. candidates for an intensive life science and pharma consulting program
Worked in a team of 4 to perform market sizing, uptake modeling, and revenue prediction for a novel drug

MIT Department of Biological Engineering | Cambridge, MA (09/2013 – 12/2013)

Teaching Assistant for Fundamentals of Drug Development

Worked with local biotech and pharma thought leaders to plan guest lectures and evaluate case studies
Designed and led weekly recitation sessions, and created and graded regular assignments for 30 students
Mentored students and served as a writing coach for final projects on drug development case studies

MIT Department of Biological Engineering | Cambridge, MA (09/2010 – 12/2011)

Teaching Assistant for Analysis of Biological Networks

Conceived, wrote, and graded case-based homework problems and exam questions for 25 Ph.D. students
Designed and presented exam preparation sessions and in-class lectures on landmark publications
Rated best of the 3 instructors for presentation quality by students in course evaluations 2 years in a row

Technical: animal models, antibiotic resistance, bacterial pathogenesis, biomarkers, diagnostics, global health, infectious disease, inflammation, immunology, metabolomics, next-gen sequencing, PK/PD and ADME-Tox
Clinical: asthma, COPD, ACO, CRSwNP, EGPA, HES, GINA, GOLD, NHLBI EPR4, RSV, spirometry
Laboratory: cell culture, chromatography (HPLC, LC-MS/MS), flow cytometry, mass spectrometry (QTOF, QQQ, MALDI)
Computer: GraphPad Prism, LaTeX, MassHunter, Mathematica, MATLAB, MS Office, Sharepoint, (X)HTML and CSS

GSK Field Medical Excellence Award – 2023
GSK Ahead Together Award (formerly IPTc Award) x4 – 2018, 2019, 2020, 2022
AAAS/Science Program for Excellence in Science – 2014
Siebel Scholars Award – 2013 to 2014
National Institute of Environmental Health Sciences Training Grant – 2011 to 2014
MIT Sloan Sales Club Bold Sell Competition Winner – 2011
National Science Foundation Graduate Research Fellowship – 2009 to 2011
Barry M. Goldwater Scholarship – 2007 to 2008
Phi Beta Kappa and Phi Kappa Phi Honor Societies, Junior Year Inductee – 2007
University of Mississippi Carrier Foundation Scholarship – 2004 to 2008
National Merit Scholarship Finalist – 2004
Eagle Scout with Boy Scout Troop 911 in Brookhaven, MS – 2003